(Senior) Research Associate – Protein Science (gn)

As part of our Protein Science team within the Antibody Discovery and Development Department, you will focus on the expression of recombinant proteins, antibodies and multispecific molecules in mammalian expression systems. You will advance the development of our transient expression platform, driving the discovery and development of innovative large‑molecule biopharmaceuticals. 

Your responsibilities will include:

• Plan and execute transient transfections in HEK and CHO - at various research scales
• Develop and optimize our transient expression platforms: process, scale-up, yield, and quality
• Run the molecular biology behind it: cloning and plasmid DNA prep at transfection scale
• Contribute to construct design and feasibility assessment 
• Step in as dedicated backup for protein purification and downstream processing
• Support analytics: Characterization of recombinant proteins using state-of-the-art biochemical and biophysical methods (SDS-PAGE, LAL Assay, HPLC) 
• Take responsibility for protein science lab equipment and infrastructure
• Carefully evaluate, interpret, and document results in electronic lab journals and databases
• Present data in internal meetings

You are the ideal candidate for this position if you bring the following:

• You hold a vocational qualification as CTA, BTA, MTA or an equivalent university degree in a relevant field; at least 4 years of professional laboratory experience is preferred
• You have in-depth experience in mammalian cell culture and transient transfection (HEK, CHO) 
• You have solid experience in cloning and molecular biology techniques; experience in construct design is a plus
• You consider downstream processing and adjacent analytical methods as a welcome variety of your daily business
• You pay attention to detail in experimental execution and documentation and have solid knowledge of relevant lab techniques and equipment, as well as standard laboratory and MS Office software
• You are a well-organized, reliable team player with a hands-on mentality and strong communication skills
• You work independently and efficiently, and adapt quickly to changing demands in a collaborative environment
• You are proficient in English, both spoken and written

We are a clinical-stage biotechnology company with around 45 employees, driven by a shared purpose: to transform cancer treatment for patients. We work with flat hierarchies and short decision-making processes, in a welcoming and trusting environment where real progress comes from working together. What you can expect from us:

• Work that matters: your work feeds directly into our pipeline of cancer immunotherapies, from multifunctional antibodies to T cell engagers on their way to the clinic
• Real impact in a small team: your work is visible and you take on responsibility early
• A culture of curiosity, integrity, and collaboration: we value diverse perspectives, open communication, and a hands-on mindset, in an environment where people grow together
• On top of that: 30 days of vacation, flexible working hours, and support for a job bike or Deutschlandticket